Belgian Journal of Paediatrics
Pilomatrixoma: Variation in Presentation. Case Report
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Keywords

Pilomatrixoma
Hair Follicle
Skin Neoplasms
Mutation
Child

Categories

How to Cite

Vanwymelbeke, J., Cornelis, A.-S., De Maeseneer, H., & Van Gysel, D. (2026). Pilomatrixoma: Variation in Presentation. Case Report. Belgian Journal of Paediatrics, 28(1), 80–82. Retrieved from https://belgjpaediatrics.com/index.php/bjp/article/view/416

Abstract

A pilomatrixoma, or benign calcifying epithelioma of Malherbe, is a benign skin tumor that is usually found in the head and neck region. It primarily affects children and adults over 50 years of age and presents as a solitary pink-to-purple lesion less than 1cm. Clinical diagnosis is often straightforward and can be confirmed by a combination of ultrasound imaging and histopathological examination. However, variability in clinical presentation can complicate the diagnosis of pilomatrixoma. Here, we present two atypical cases in children that could easily lead to misdiagnosis. We discuss clinical presentation, diagnostic confirmation and treatment approaches.

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