Abstract
This report highlights the case of a 3-year-old girl with Kawasaki disease and concurrent Mycoplasma pneumoniae infection. Treatment with intravenous immunoglobulin, high-dose aspirin and corticosteroids led to clinical remission and resolution of cardiac abnormalities. This case highlights the need for timely recognition of KD and co-infection, and stresses the role of early, tailored management in preventing serious complications. Co-infection, pathophysiological hypotheses and pharmacogenetics are briefly explored.