Belgian Journal of Paediatrics
Case series of Multisystem Inflammatory Syndrome in Children (MIS-C) after a SARS-CoV-2 infection

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Keywords

multisystem inflammatory syndrome in children and adolescents
MIS-C
paediatric multisystem inflammatory syndrome temporally associated with SARS-Co-V-2
PIMS-TS
COVID-19
SARS-Co-V-2
severe
cute respiratory syndrome coronavirus 2

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How to Cite

Geeurickx, M., Vermaning, S., Crijnen, T., Gerard, I., Vanderschraeghe, E., & Raaijmakers, A. (2023). Case series of Multisystem Inflammatory Syndrome in Children (MIS-C) after a SARS-CoV-2 infection . Belgian Journal of Paediatrics, 24(2), 111–115. Retrieved from http://belgjpaediatrics.com/index.php/bjp/article/view/71 (Original work published December 20, 2022)

Abstract

Multisystem inflammatory syndrome in children (MIS-C) is an entity in which children develop fever, raised inflammatory parameters, abdominal complaints and/or Kawasaki-like symptoms with signs of decreased cardiac function, weeks after a primary infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).  Complications include shock and coronary artery aneurysms. Our cases are in line with current evidence that clinical presentation of MIS-C is extremely variable, and evolution is favourable after treatment with intravenous immunoglobulins. Further research is necessary to substantiate current guidelines and to analyse possible links we have encountered between developing MIS-C and ethnic background, environment, and specific SARS-CoV-2 strains.

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